National Institutes of Health Grants
The National Institutes of Health (NIH), a part of the U.S. Department of Health and Human Services, is the primary Federal agency for conducting and supporting medical research. NIH grants are awarded through a highly competitive grant process. The following are current and recently completed grants awarded to Legacy Health scientists.
Biomechanics
Michael Bottlang, PhD, Principal Investigator
R21AR053958
"Evaluating and improving an emergent technology for fixation of bone fractures"
07/01/2006 - 05/31/2008
Current Funding: $207,240
Abstract
Neurobiology - RS Dow Neurobiology Labs
Detlev Boison, PhD, Principal Investigator
R01NS058780
"Adenosine-releasing brain implants for epilepsy therapy"
01/01/2008 – 11/30/2011
Current Year Funding: $323,409
Abstract
Detlev Boison, PhD, Principal Investigator
R21NS057475
"Adenosine kinase as novel therapeutic target to prevent acquired epilepsy"
04/01/2008 – 03/31/2010
Current Year Funding: $172,484
Abstract
Detlev Boison, PhD, Principal Investigator
R21NS057538
"Adenosine kinase as therapeutic target to induce and maintain ischemic tolerance"
04/01/2008 – 03/31/2010
Current Year Funding: $172,484
Abstract
Detlev Boison, PhD, Principal Investigator
R01MH083973
"Adenosine and schizophrenia: mechanisms and therapies"
03/20/2009 - 01/31/2014
Current Year Funding: $345,925
Abstract
Detlev Boison, PhD, Principal Investigator
R01NS061844
"Astrocyte dysfunction in epileptogenesis: the role of adenosine"
04/15/2009 - 03/31/2013
Current Year Funding: $310,472
Abstract
Theresa Lusardi, PhD, Principal Investigator
F32NS053257
"Sensitization in primary and secondary brain injury"
07/15/2005 – 07/14/2008
Current Year Funding: $53,992
Abstract
Robert Meller, DPhil, Principal Investigator
R21NS054023
"Rapid ischemic tolerance: Ubiquitin-mediated structural reorganization"
09/01/2006 – 06/30/2008
Current Year Funding: $169,319
Abstract
Robert Meller, DPhil, Principal Investigator
R01NS059588
"Rapid ischemic tolerance: Synaptic re-organization and reduced excitotoxicity"
09/30/2008 – 08/31/2013
Current Year Funding: $344,969
Abstract
Julie A. Saugstad, PhD, Principal Investigator
R01 NS064270
"Role of MicroRNAs in ischemic tolerance"
05/01/2010 - 04/30/2013
Current Year Funding: $306,000
Abstract
Julie A. Saugstad, PhD, Principal Investigator
R21NS054220
"Role of MicroRNAs in ischemic tolerance"
08/02/2006 – 06/30/2008
Current Year Funding: $203,182
Abstract
Julie A. Saugstad, PhD, Principal Investigator
R01NS050221
"Neuroprotection by novel regulators of mGluR signaling"
12/16/2005 – 11/20/2009
Current Year Funding: $304,773
Abstract
Roger P. Simon, MD, Principal Investigator
R01NS047622
"Molecular determinants of epileptic brain injury"
07/01/2005 – 06/30/2009
Current Year Funding: $339,799
Abstract
Roger P. Simon, MD, Principal Investigator
R01NS039016
"Molecular mechanisms of seizure-induced brain injury"
07/01/1999 – 06/30/2010
Current Year Funding: $339,864
Abstract
Roger P. Simon, MD, Principal Investigator
R01NS050610
"Acid-sensing ion channels and ischemic brain injury"
05/24/2005 – 04/30/2010
Current Year Funding: $333,286
Abstract
Roger P. Simon, MD, Principal Investigator
P01NS035965
"Molecular mechanisms of ischemia"
03/01/1998 – 04/30/2008
Current Year Funding: $1,247,891
Abstract
Roger P. Simon, MD, Principal Investigator
R01NS024728
"Cell excitation in ischemic brain injury"
07/01/1988 – 12/31/2010
Current Year Funding: $343,006
Abstract
Zhigang Xiong, MD, PhD, Principal Investigator
R01NS047506
"Acid-sensing channels as novel target for brain ischemia"
07/01/2004 – 05/31/2011
Current Year Funding: $321,300
Abstract
Zhigang Xiong, MD, PhD , Principal Investigator
R01NS049470
"A novel cation channel in excitatory neuronal injury"
04/01/2005 – 03/31/2009
Current Year Funding: $322,594
Abstract
An Zhou, PhD , Principal Investigator
R01NS046560
"Brain ischemia attenuates neuropeptide biosynthesis"
12/15/2004 – 11/30/2008
Current Year Funding: $305,877
Abstract
An Zhou, PhD , Principal Investigator
R21EY017345
"Neuropeptide processing and ischemic retina injury"
04/01/2006 – 03/31/2008
Current Year Funding: $174,780
Abstract
Neuromuscular
Jose Ochoa, MD, PhD, Principal Investigator
R01NS048932
"Primary C nociceptors and C sympathetics in CRPS"
06/15/2006 – 05/31/2010
Current Year Funding: $383,118
Abstract
Neurotology
P. Ashley Wackym, MD, Principal Investigator
R01DC02971
"Molecular Basis of Vestibular Efferent Function"
07/01/1995 - 03/31/2011
Current Year Funding: $343,506
Abstract
Ophthalmology – Devers Research - Discoveries in Sight Research Laboratories
See also Devers Research
Claude F. Burgoyne, MD, Principal Investigator
R01EY01EY011610
"IOP-related force and failure in the optic nerve head"
07/01/1998 – 06/30/2012
Current Year Funding: $707,574
Abstract
George A. Cioffi, MD, Principal Investigator
U10EY010362
"Ocular hypertension treatment study (OHTS)"
01/01/1994 – 12/31/2008
Current Year Funding: $215,573
Abstract
Shaban Demirel, PhD, Principal Investigator
R01EY019674
"Predicting the rate of progression in glaucoma"
09/30/09 - 08/31/2014
Current Year Funding: $382,500
Abstract
J. Crawford Downs, PhD, Principal Investigator
R21EY018152
"3D reconstruction of optic nerve heads"
09/30/2007 – 08/03/2009
Current Year Funding: $232,000
Abstract
J. Crawford Downs, PhD,
and Christopher A. Girkin, MD (Univ of Alabama Birmingham), Principal Investigators
R01EY018926
“Age-related changes in optic nerve head structure and biomechanics”
04/01/2008 – 03/31/2012
Current Year Funding: $343,283
Abstract
J. Crawford Downs, PhD,
and Christopher A. Girkin, MD (Univ of Alabama Birmingham), Principal Investigators
R01EY019333
"Racial Variations in Optic Nerve Head Structure and Biomechanics"
12/01/2008 - 11/30/2011
Current Year Funding: $320,085
Abstract
Brad Fortune, OD, PhD, Principal Investigator
R01EY019327
"Axonal cytoskeletal changes in experimental glaucoma"
09/01/2009 - 08/31/2013
Current Year Funding: $344,250
Abstract
Steven L. Mansberger, MD, MPH, Principal Investigator
K23EY015501
"The Northwest tribal vision project"
06/01/2004 – 05/31/2009
Current Year Funding: $248,020
Abstract
Lin Wang, MD, Principal Investigator
R01EY019939
"Dynamic and Static Autoregulation Impairment in the Optic Nerve Head of Glaucoma"
08/01/2010 - 06/30/2015
Current Year Funding: $382,500
Abstract
Lin
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