- At least 18 years old
- Diagnosed with type 2 diabetes mellitus
- HbA1c of 7.1% to 11.0%, inclusive, at screening
- Has stable body weight, i.e., not varying by >3% for at least 3 months prior to screening
- Fasting plasma glucose concentration <280 mg/dL (15.5 mmol/L) at screening
- Body mass index of <45 kg/m2 at screening
- Has been treated with a stable regimen of ≥1500 mg/day metformin for a minimum of 2 months prior to Visit 1 (Screening)
Exclusion Criteria - contact study coordinator.