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ACTIVATED PROTEIN C RESISTANCE

Mnemonic

APC RES

Synonym

APC

Specimen Collection Requirements

Collect

Plasma, light blue (3.2% [0.109 M] sodium citrate) top tube

Handling

Platelet-poor plasma. For detailed specimen collection and handling requirements, refer to Coagulation Specimen Collection Guidelines. CRITICAL FROZEN. Separate samples must be submitted when multiple tests are ordered.

Preferred Volume

1.5 mL

Minimum Volume

1.0 mL

Transport

Frozen

Stability

Ambient: 4 hours; Refrigerated: Unacceptable; Frozen (at -20°C): 3 months; Frozen (at -70°C): 6 months

Testing Information

Performed

Mon - Sat

Reported

2-4 days

Method

Electromagnetic Mechanical Clot Detection

Referral Lab

ARUP (30127)

Reference Values

Reference Values

2.0 or greater
Ratios less than or equal to 2.00 suggest APC resistance.

Comments

This method uses factor V deficient plasma; therefore, APC resistance due to a nonfactor V mutation will not be detected.  Extreme factor V deficiency may cause an abnormal ratio.

CPT Codes

85307

Last Updated: Thursday, September 21, 2017 01:23:30 PM


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