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BENZODIAZEPINE , QUANTITATIVE, SERUM

Synonym

Alprazolam (Xanax) -  Lorazepam (Ativan) - Nordiazepam, Oxazepam (Serax) - Temazepam (Restoril) - Diazepam (Valium)

Includes

Lorazepam, Nordiazepam, Oxazepam, Temazepam, Alprazolam, Diazepam

Alprazolam reported QUALITATIVE ONLY

Specimen Collection Requirements

Collect

Serum or Plasma, one 7.0 mL red, 4.0 mL dark green (sodium heparin), or 4.0 mL lavender (EDTA) top tube. SST and PST tubes are NOT recommended.

Handling

Allow serum to clot completely at room temperature (minimum 30 minutes). Centrifuge and separate serum or plasma from cells ASAP.

Preferred Volume

2 mL Serum or Plasma

Minimum Volume

0.25 mL Serum or Plasma (Whole Blood draw 1.0 mL)

Transport

Refrigerated (2-8°C)

Rejection Criteria

Frozen whole blood, gross hemolysis, specimens collected in PST or SST tubes that were not removed from the gel separator within 24 hours

Stability

Ambient (20-25°C): 2 weeks; Refrigerated (2-8°C): 2 months; Frozen (at or below -20°C): 2 months

Testing Information

Performed

Tue, Thu

Reported

1-5 days

Method

Liquid Chromatography Tandem Mass Spectrometry

Reference Values

Reference Values

Diazepam, Nordiazepam, Oxazepam, Temazepam, Lorazepam, Alpha Hydroxy Alprazolam: Not Detected  < 20 ng/mL

Alprazolam: Not Detected < 2 ng/mL

Therapeutic Range

Toxic Levels

Comments

Identification of specific drug provided.

CPT Codes

80347

Last Updated: Tuesday, August 1, 2017 08:15:38 AM


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