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FECAL CALPROTECTIN ELISA

Mnemonic

FE CALPROT

Synonym

Calprotectin, Fecal - Stool Calprotectin

Guidelines

Fecal Calprotectin is an indicator of the presence of neutrophils in stool and is not specific for inflammatory bowel disease (IBD). Other intestinal ailments including GI infections and colorectal cancer can result in elevated concentrations of calprotectin. The diagnosis of IBD cannot be established solely on the basis of a positive calprotectin result. Patients with IBD fluctuate between active and inactive stages of disease. Calprotectin results may also fluctuate.

Specimen Collection Requirements

Collect

Random stool

Handling

1-5 grams stool in a clean non-preservative container

Preferred Volume

5 grams

Minimum Volume

1 gram

Transport

Refrigerated

Rejection Criteria

Specimens in media or preservatives, stool samples in diapers will not be accepted

Stability

Samples may be stored at 2-8⁰C for up to 4 days, then frozen at -20⁰C for 2 months.

Testing Information

Performed

Tues, Thurs

Reported

2-7 days

Method

Quantitative Enzyme-Linked Immunosorbent Assay

Reference Values

Reference Values

≤ 50 mg/kg

Comments

GI bleeding of as much as 10 mL per day will increase the fecal calprotectin concentration by only 15 µg/g.

CPT Codes

83993

Last Updated: Thursday, January 5, 2017 03:40:36 AM


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