ADULT: ATTN FISH, PEDIATRIC: ATTN CYGEN
16q22 - inv(16)(p13q22) - t(16;16)(p13;q22)
This probe is designed to detect translocations/variant rearrangements involving CBFβ (Core Binding Factor Beta subunit) gene, such as pericentric inversion of chromosome 16. This inversion is a subtle chromosome abnormality seen in Acute Myeloid Leukemia (M4) cases.
Specimen Collection Requirements
Fluorescence In Situ Hybridization (FISH)
Professional interpretation provided by Cascade Pathology Services.
inv(16)(p13q22), t(16;16)(p13;q22) and del(16)(q22) are also seen in acute non lymphoblastic leukemia (ANLL) or myelodysplastic syndromes (MDS). This probe is part of the Acute Myeloid Leukemia Panel (Adult and Pediatric), probes can be ordered individually.
Tuesday, June 6, 2017 11:12:18 AM
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