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FISH PROBE: D20S108

Mnemonic

ADULT: ATTN FISH, PEDIATRIC: ATTN CYGEN

Synonym

(20q12) - Del20q

Guidelines

This probe detects deletions on the long arm of chromosome 20 (20q12), where a tumor suppressor gene resides. Deletion of 20q12 is associated with Myelodysplastic Syndrome and confers favorable prognosis.

Specimen Collection Requirements

Handling

Testing Information

Performed

Mon - Fri

Reported

7 days

Method

Fluorescence In Situ Hybridization (FISH)

Reference Values

Reference Values

Professional interpretation provided by Cascade Pathology Services.

Comments

Deletion of the long arm of chromosome 20 represents the most common chromosomal abnormality associated with myeloproliferative disorders (MPD’s).   Besides Myelodysplastic Syndromes (MDS) it is also found in Acute Myeloid Leukemias (AML).  This probe is part of the Myelodysplastic Syndrome Panel, probes can be ordered individually.

CPT Codes

ADULT: 88377 x 1

Last Updated: Tuesday, June 6, 2017 11:12:21 AM


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