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FISH PROBE: ETV6/RUNX1-ES (TEL/AML1-ES)

Mnemonic

ATTN CYGEN

Synonym

t(12;21)(p13;q22) - ETV6/RUNX1 ES

Guidelines

This probe detects the t(12;21) seen in pediatric precursor B-lineage ALL and confers a favorable prognosis. This chromosomal abnormality is considered cryptic by conventional cytogenetics, thus reinforces the need to perform this test. Amplification of AML1, which is associated with a poor outcome, is also detectable by this probe set.

Specimen Collection Requirements

Handling

Testing Information

Performed

Mon - Fri

Reported

7 days

Method

Fluorescence In Situ Hybridization

Reference Values

Reference Values

Professional interpretation provided by Cascade Pathology Services.

Comments

This probe is part of the Pediatirc Acute Lymphoblastic Leukemia Panel, probes can be ordered individually.

Last Updated: Tuesday, June 6, 2017 11:12:27 AM


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