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HEAT SHOCK PROTEIN 70 IgG

Mnemonic

HSP70 AB

Synonym

Inner Ear Antigen - Inner Ear Heat Shock Protein - Inner Ear Antibody

Guidelines

The presence of HSP70 IgG antibodies may be useful in predicting corticosteroid responsiveness in a subset of patients with autoimmune inner ear disease (AIED) characterized by idiopathic rapidly progressive sensorineural hearing loss (SNHL). HSP70 IgG antibodies are also associated with a number of autoimmune diseases and have also been reported in apparently healthy individuals. A negative result does not rule out response to treatment or to a diagnosis of AIED.

Specimen Collection Requirements

Collect

Serum, one serum separator or plain red top tube

Handling

Do not use anticoagulants or preservatives.

Preferred Volume

0.5 mL

Minimum Volume

0.1 mL

Transport

Refrigerated

Rejection Criteria

Hemolyzed or lipemic specimens, specimens with large clots present or bacterial growth, specimens collected with anticoagulants or preservatives

Stability

Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year

Testing Information

Performed

Sun, Tue, Thu

Reported

2-8 days

Method

Qualitative Immunoblot

Referral Lab

ARUP (2013590)

Reference Values

Reference Values

Negative

CPT Codes

83516

Last Updated: Thursday, January 5, 2017 03:41:09 AM


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