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LEAD AND ZINC PROTOPORPHYRIN

Mnemonic

ZINC/LEAD

Synonym

Blood Lead Level - BLL - Pb - Venous Blood Lead - ZPP - ZnPP® - ZPPH

Includes

Blood Lead and Zinc Protoporphyrin

Specimen Collection Requirements

Collect

Preferred: Venous Whole Blood, one certified lead-free tube such as one 6.0 mL royal blue (K2EDTA or Na2EDTA) top tube. Also acceptable: Venous whole blood, one 4.0 mL lavender (EDTA) top tube. PROTECT FROM LIGHT.

NOTE: All elevated Lead blood levels collected in a non-certified lead-free tube (i.e., EDTA lavender top tube) will be run with the following disclaimer: “Specimen was collected in a non-certified lead-free tube. Recommend confirming elevated level of blood lead with a second specimen collected in a lead-free tube."

Handling

Guard the specimen against environmental contamination. Keep the specimen sealed in the original container. PROTECT FROM LIGHT. Do not separate the plasma from the red blood cells.

Preferred Volume

3.0 mL whole blood

Minimum Volume

1.2 mL whole blood

Transport

Refrigerated (2-8°C), PROTECT FROM LIGHT

Rejection Criteria

Serum and plasma specimens; Whole blood collected in tube with anticoagulant other than EDTA; Frozen specimens; Grossly hemolyzed specimens, Specimens not protected from light

Stability

Room Temperature (18-26°C): 24 hours; Refrigerated (2-8°C): 7 days; Frozen (≤ -20°C): Unacceptable

Testing Information

Note

Elevated blood lead levels may be due to skin or collection-related contamination, including use of non-certified lead free tubes. Elevated levels of blood lead should be confirmed with a second specimen collected in a lead-free tube.

Performed

Mon, Wed, Fri

Reported

24-72 hours

Method

Atomic Absorption Spectroscopy - Graphite Furnace, Hematofluorometry

Reference Values

Reference Values

Toxic Levels

Lead: See Recommended Actions for Blood Lead Levels

ZnPP: Not established

Comments

All blood lead levels are reported to the Oregon or Washington Health Division.

CPT Codes

Lead: 83655, ZnPP: 84202

Last Updated: Thursday, January 5, 2017 03:41:21 AM


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