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RUBELLA ANTIBODY, IgG

Mnemonic

RUB IGG

Synonym

German Measles Immune Status

Guidelines

Used to determine immune status for Rubella virus.

Specimen Collection Requirements

Collect

Serum, one 5.0 mL gold (SST) or 7.0 mL red top tube

View image for Supply Item Number - 101235 or 101192

Handling

Allow serum tubes to clot completely at room temperature (minimum - SST: 30 minutes, red top tubes: 60 minutes). Centrifuge and separate serum from cells ASAP. 

Preferred Volume

1.0 mL Serum

Minimum Volume

0.25 mL Serum (Whole Blood 0.6 mL minimum draw)

Transport

Refrigerated (2-8°C)

Rejection Criteria

Grossly hemolyzed or plasma specimens, specimens that have undergone more than 3 freeze-thaws

Stability

AFTER SEPARATION FROM CELLS: Room Temperature (18-26°C): 8 hours; Refrigerated (2-8°C): 48 hours; Frozen (≤ -20°C): 2 months

Testing Information

Performed

Mon - Fri and a single run on the weekend

Reported

24-72 hours

Method

Chemiluminescent Immunoassay

Reference Values

Reference Values

Interpretation

Comments

Nonreactive

Patients are considered to have an absence of immunity.

Equivocal

Studies suggest that vaccinated individuals having these low levels of anti-rubella IgG do show a secondary immune response following re-vaccination but have not been challenged with wild rubella virus.  A follow-up sample should be taken to further evaluate immune status.  If the repeat sample is still equivocal, the sample may require testing by alternate methods.

Reactive

Patients are considered to have anti-Rubella IgG present and indicate acute or past infection, or vaccination.

CPT Codes

86762

Last Updated: Monday, March 6, 2017 04:21:22 PM


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