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TISSUE TRANSGLUTAMINASE ANTIBODY, IgA

Mnemonic

TTG IGA

Synonym

TTG - tTG-IgA - tTG-IgA Antibody

Includes

Tissue Transglutaminase Antibody, IgA ELISA and Interpretation

Guidelines

The endomysial antigen has been identified as the protein cross-linking enzyme known as tissue transglutaminase. Detection of tissue transglutaminase antibodies is an aid in the diagnosis of certain gluten-sensitive enteropathies, such as celiac disease and dermatitis herpetiformis. Human tTG antigen is utilized in this assay.

Specimen Collection Requirements

Collect

Serum, one gold (SST) top tube

View image for Supply Item Number - 101235

Handling

Allow to clot, centrifuge and separate serum from cells immediately. Pour into a plastic tube. Refrigerate at 2-8°C. Freeze at -20°C if specimen cannot be assayed within 48 hours.

Preferred Volume

1.0 mL

Minimum Volume

0.5 mL

Transport

Refrigerated (2-8°C) or frozen on dry ice

Rejection Criteria

Plasma, microbially contaminated, heat-treated or specimens containing visible particulate, grossly hemolyzed or lipemic specimens should be avoided

Stability

AFTER SEPARATION FROM CELLS: Ambient (20-25°C): 8 hours; Refrigerated (2-8°C): 48 hours; Frozen (at or below -20°C): 2 months

Testing Information

Performed

Mon, Wed, Fri

Reported

24-72 hours

Method

Enzyme-Linked Immunosorbent Assay

Reference Values

Reference Values

Less than or equal to 19.9 units

CPT Codes

83516

Last Updated: Thursday, January 5, 2017 03:41:41 AM


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