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ZINC PROTOPORPHYRIN

Mnemonic

ZPP

Synonym

FEP – Zinc Protoporphyrins Whole Blood – ZnPP - ZPPH

Includes

Zinc Protoporphyrin (ZPP)
Zinc Protoporphyrin-to-Heme Ratio (ZPPH)
 

Specimen Collection Requirements

Collect

Whole Blood, one 3.0 mL lavender (EDTA) or 6.0 mL royal blue (EDTA) top tube

Handling

PROTECT FROM LIGHT during collection, storage and shipment. Do not separate the plasma from the red blood cells.

Preferred Volume

1.0 mL Whole Blood

Minimum Volume

0.5 mL Whole Blood

Transport

Refrigerate (2-8°C), protect from light

Rejection Criteria

Hemolyzed, frozen or clotted specimens

Stability

Room Temperature (18-26°C): 14 days; Refrigerated (2-8°C): 20 days; Frozen (≤ -20°C): Unacceptable

Testing Information

Performed

Mon, Wed, Fri

Reported

24-72 hours

Method

Hematofluorometry

Reference Values

Reference Values

Zinc Protoporphyrin:  0-37 µg/dL
Zinc Protoporphyrin-to-Heme Ratio:  0-69 µmol ZPP/mol Heme
 

CPT Codes

84202

Blood Product

Comment

Legacy reports ZPP and ZPPH assuming a hematocrit of 42%.  Interpret results with caution if the patient’s hematocrit is significantly different (i.e., pediatric or anemic patients).

Last Updated: Thursday, October 19, 2017 06:13:00 AM


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