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ZONISAMIDE

Mnemonic

ZONI

Specimen Collection Requirements

Collect

Serum or Plasma, one red (non SST) or lavender (EDTA) top tube

Handling

Separate serum or plasma from cells within 2 hours of collection. Transfer 1.0 mL serum or plasma to an aliquot tube

Preferred Volume

1.0 mL

Minimum Volume

0.5 mL Serum or Plasma (Whole blood, 1.2 mL minimum draw)

Transport

Refrigerated

Rejection Criteria

Whole blood, gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution) top tube

Stability

Ambient: 1 week; Refrigerated: 1 week; Frozen: 6 weeks

Testing Information

Performed

Mon - Fri

Reported

2-6 days

Method

Quantitative EMIT Immunoassay

Referral Lab

ARUP (97908)

Reference Values

Therapeutic Range

Therapeutic range not well established.

Comments

The proposed therapeutic range for seizure control is 10-40 µg/mL.  Concentrations that exceed 80 µg/mL may contribute to adverse effects.  Pharmacokinetics varies widely, particularly with co-medications and/or compromised renal function.

CPT Codes

80203

Last Updated: Friday, September 29, 2017 08:51:14 AM


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