FIRST AID Advice for Anaphylaxis - Epinephrine (pending EMS arrival):

• If the patient has an epinephrine autoinjector, the patient should use it now.
• Use the autoinjector on the upper outer thigh. You may give it through clothing if necessary.

Epinephrine is available in autoinjectors under trade names: Epi-Pen, Epi-Pen Jr, and Twinject. Epi-Pen is a single injection. Twinject has a second injection that can be used if there is no improvement after 5 minutes.