Questions
- Docosanol cream (Abreva)seems to reduce severity, pain and duration of cold sores (Sacks 2001). Docosanol is FDA approved in the United States. Ask your physician's opinion.
- Topical (cream) prescription treatment with Pencylcovir 1%: Use of this cream four times daily has been shown to reduce the severity, pain and duration of cold sores in adults (Spruance 1997). It is more expensive than docosanol.
- Oral (pills) prescription treatment - Available oral anti-viral medications include acyclovir (Zovirax), famcyclovir (Famvir), and valacyclovir (Valtrex). There may be some modest benefit obtained from using these medications; these medications may shorten symptom duration by 1 day and reduce symptoms. However, the research is not conclusive and such treatment is not standard practice (Emmert 2000). You will need to discuss this with your physician.
