Widespread Hives - Take Antihistamine Medication

• Take an antihistamine like over-the-counter loratadine (e.g., Claritin, Alavert) for widespread hives that itch. The adult dosage of loratadine is 10 mg by mouth once each day. Continue the antihistamine until the hives have been gone for 24 hours. Any antihistamine will do - but some cause more drowsiness than others. Loratidine is a newer (second generation) antihistamine and it causes less sedation than diphenhydramine (Benadryl) or chlorpheniramine (Chlortrimeton).
  • Do not take anthistamines if you have prostate problems.
  • Antihistamines may cause sleepiness. Do not drink, drive or operate dangerous machinery while taking antihistamines.
  • Read the package instructions thoroughly on all medications that you take.