ADULT: ATTN FISH, PEDIATRIC: ATTN CYGEN
t(9;22)(q34;q11.2) - Philadelphia Chromosome - t(9;22)
This dual fusion tricolor probe is designed to detect the classical t(9;22) and atypical rearrangements involving ABL1 and BCR genes on chromosome 9 and 22, respectively. This test is used for primary diagnosis or to monitor minimal residual diseases in CML patients.
Specimen Collection Requirements
Fluorescence In Situ Hybridization (FISH)
Professional interpretation provided by Cascade Pathology Services.
Diagnosis of some chronic myeloproliferative diseases such as polycythemia vera, essential thromobocythemia require exclusion of BCR-ABL1 gene rearrangement. In Acute Myeloid Leukemia/Acute Lymphoblastic Leukemia and in precursor T-lymphoblastic leukemia/lymphomas, BCR-ABL1 gene rearrangement and ABL1 gene amplification can be detected, respectively. This probe is part of the Acute Myeloid Leukemia Panel (Adult), probes can be ordered individually.
Thursday, January 5, 2017 03:41:59 AM