ACTIVATED PROTEIN C RESISTANCE
Specimen Collection Requirements
Plasma, light blue (3.2% [0.109 M] sodium citrate) top tube
Platelet-poor plasma. For detailed specimen collection and handling requirements, refer to Coagulation Specimen Collection Guidelines. CRITICAL FROZEN.
Separate samples must be submitted when multiple tests are ordered.
Ambient: 4 hours; Refrigerated: Unacceptable; Frozen (at -20°C): 3 months; Frozen (at -70°C): 6 months
Electromagnetic Mechanical Clot Detection
2.0 or greater
Ratios less than or equal to 2.00 suggest APC resistance.
This method uses factor V deficient plasma; therefore, APC resistance due to a nonfactor V mutation will not be detected. Extreme factor V deficiency may cause an abnormal ratio.
Thursday, January 5, 2017 03:41:55 AM