ANCA VASCULITIS (MPO/PR3)

Mnemonic

<b><span style='color:red'><u>ANCAVASC</span></u></b>

Synonym

MPO/PR-3 (ANCA) Antibodies

Specimen Collection Requirements

Collect

One SST Tube

Handling

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL)

Transport

Refrigerated.

Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Testing Information

Note

Approximately 90% of patients with a P-ANCA pattern by IFA have antibodies specific for MPO. Approximately 85% of patients with a C-ANCA pattern by IFA have antibodies specific for PR3.

Performed

Sun-Sat

Method

Semi-Quantitative Multi-Analyte Fluorescent Detection

Referral Lab

ARUP (0050707)

Reference Values

Reference Values

Myeloperoxidase Antibody (MPO): Negative: 19 AU/mL or less Equivocal: 20-25 AU/mL Positive: 26 AU/mL or greater Serine Protease 3 Antibody (PR3) Negative: 19 AU/mL or less Equivocal: 20-25 AU/mL Positive: 26 AU/mL or greater

CPT Codes

83516 Myeloperoxidase Ab; 83516 Serine Protease 3

Last Updated: Thursday, January 5, 2017 03:41:59 AM