ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES VASCULITIS PANEL, SERUM

Mnemonic

ANCAVASC

Includes

Myeloperoxidase Antibody, Proteinase 3 Antibody (PR3), Cytoplasmic Neutrophilic Antibody if reflexed

Guidelines

Use when evaluating patients suspected of having autoimmune vasculitis, both Wegener's granulomatosis and microscopic polyangiitis.

Specimen Collection Requirements

Collect

Serum, plain, red or gold (SST) top tube

Preferred Volume

1.0 mL

Minimum Volume

0.5 mL

Transport

Refrigerated

Rejection Criteria

Plasma, grossly lipemic or hemolyzed specimens

Stability

Refrigerated 21 days; Frozen 21 days

Testing Information

Performed

Mon - Sat

Reported

3-4 days

Method

Multiplex Flow Immunoassay/Indirect Immunofluorescence

Referral Lab

Mayo Medical Laboratory (VASC)

Reference Values

Reference Values

Interpretation provided.

Comments

If myeloperoxidase (MPO) antibody or PR3 antibody is ≥0.4 U, then cytoplasmic neutrophilic antibodies will be performed at an additional charge.

CPT Codes

83516 x2, 86255 and 86256 if reflexed

Last Updated: Thursday, January 5, 2017 03:41:59 AM