AT III

Mnemonic

<b><span style='color:red'><u>AT3</span></u></b

Synonym

ANTITHROMBIN III ACTIVITY, Heparin Co-Factor -AT III Functional Activity

Guidelines

Measures activity of AT III present in plasma. Values may decrease in inherited and acquired deficiencies and liver disease. Heparin and Coumadin do not interfere with the assay but may alter physiologic values. Call Special Coagulation Lab (503) 413-5119 for STAT requests, or minimal sample volumes.

Specimen Collection Requirements

Collect

Two light blue (3.2% Buffered Sodium Citrate) top tubes

Handling

See Coagulation Specimen Collection Guidelines.

Preferred Volume

Two 3.0 mL aliquots

Minimum Volume

One 3.0 mL aliquot

Transport

Ambient (20-28°C)

Rejection Criteria

Clotted samples, samples collected in containers other than 3.2% Buffered Sodium Citrate, tubes filled less than 90%, samples from patients with a Hematocrit greater than 55%, hemolyzed samples due to ex-vivo causes (i.e., difficult draw, poor sample draw), whole blood samples that were frozen before processing

Stability

WHOLE BLOOD Ambient: 4 hours PLASMA Ambient: 4 hours; Frozen: -20°C, 2 weeks, -70°C, 6 months

Testing Information

Performed

Mon, Wed, Fri

Method

Chromogenic

Referral Lab

Legacy Laboratory Services.

Reference Values

Reference Values

Varies, see report.

CPT Codes

85300

Last Updated: Thursday, January 5, 2017 03:41:58 AM