CHROMOSOMAL ANALYSIS BLOOD FOR HEMATOLOGIC DISORDERS

Mnemonic

MISC

Synonym

Karyotype - Karyotyping - Chromosomes - Chromosome Study - Cytogenetics

Guidelines

Although bone marrow is the recommended specimen for hematological disorders, whole blood with a circulating blast count of 5% or greater is an acceptable alternative. The presence of circulating blasts in the peripheral blood is critical to the success of this test. The blast count should be 5% or greater.

Specimen Collection Requirements

Collect

Whole Blood, in a dark green (preservative-free sodium heparin) top tube

Handling

Keep specimen at ambient temperature and always transport the same day or within 24 hours. See Cytogenetics, Flow Cytometry and FISH Specimens for Leukemia, Lymphoma and Other Oncology Referrals.

Preferred Volume

4.0 mL

Minimum Volume

1.0 mL

Transport

Room temperature within 24 hours of collection

Rejection Criteria

Capillary stick

Stability

Ambient: 24 hours; Refrigerated: Suboptimal, call Cytogenetics at (503) 413-4613

Testing Information

Note

Clinical information including the indication for study must accompany the specimen. This should include treatment history and a copy of the most recent CBC result.

Performed

7 days/week

Reported

7 days

Method

Classical G-Band Chromosomal Analysis

Reference Values

Reference Values

Cytogenetics interpretation provided. A computer generated karyotype is also provided with each study.
Normal range:
46,XX [number of cells analyzed], apparently normal female
46,XY [number of cells analyzed], apparently normal male

Comments

For questions regarding the report, please call (503) 413-4613.

Last Updated: Thursday, January 5, 2017 03:42:03 AM