CHROMOSOMAL ANALYSIS SKIN BIOPSY

Mnemonic

MISC

Synonym

Karyotype - Karyotyping - Chromosomes - Chromosome Study - Cytogenetics

Specimen Collection Requirements

Patient Preparation

The biopsy site should be prepared by washing with antiseptic soap and thoroughly rinsing with sterile water. A local anesthetic may be used. DO NOT use alcohol or iodine preparations, as they may affect the viablility of the cells.

Collect

A biopsy that includes the dermis

Handling

Skin punch biopsy is acceptable. Use sterile technique. Place specimen in a screw-top container and cover with sterile Hanks BSS, normal saline or RPMI transport media. Keep specimen at ambient temperature.

Minimum Volume

Approximatey 3.0 mm X 5.0 mm

Transport

Room temperature within 24 hours of collection

Rejection Criteria

SPECIMENS SUBMITTED IN OR EXPOSED TO FORMALIN. Rejection is only at the discretion of the Cytogenetics Laboratory.

Stability

Ambient: 24 hours; Refrigerated: Suboptimal, call Cytogenetics Lab at (503) 413-4613

Testing Information

Note

Clinical information including the indication for study must accompany the specimen. Requisition forms for cytogenetics studies are available upon request.

Performed

7 days/week

Reported

3-4 weeks

Method

Classical G-Band Chromosomal Analysis

Reference Values

Reference Values

Cytogenetic interpretation provided. A computer generated karyotype is also provided with each study.
Normal range:
46,XX, apparently normal female
46,XY, apparently normal male
If Genetic Counseling is needed, call (503) 413-5214.

Comments

For questions regarding the report, please call (503) 413-4613.

Last Updated: Thursday, January 5, 2017 03:42:03 AM