CONNECTIVE TISSUE DISEASES CASCADE, SERUM

Mnemonic

CTDC

Includes

Antinuclear Antibody and Cyclic Citrullinated Peptide Antibody

Specimen Collection Requirements

Collect

Serum, one gold (SST) or plain red top tube

Handling

Separate serum from cells ASAP.

Preferred Volume

1.0 mL

Minimum Volume

0.7 mL

Transport

Refrigerated

Rejection Criteria

Plasma and other body fluids, severely lipemic, contaminated and hemolyzed specimens

Stability

AFTER SEPARATION FROM CELLS: Ambient: Unacceptable; Refrigerated: 21 days; Frozen: 21 days

Testing Information

Performed

Mon - Sat

Reported

3-5 days

Method

Enzyme Immunoassay (EIA), Enzyme-Linked Immunosorbent Assay, Multiplex Flow Immunoassay

Referral Lab

Mayo Medical Laboratories (CTDC)

Reference Values

Reference Values

Interpretation provided.

Comments

If antinuclear antibodies are ≥ 3.0 U, then Antibodies to Double-Stranded DNA (ds-DNA), Extractable Nuclear Antigen Evaluation, Ribosome P and Centromere are performed at an additional charge.

CPT Codes

86038-ANA, 86200-Cyclic citrullinated peptide antibodies, IgG, 83516-Centromere (if appropriate), 83520-Ribosome (if appropriate), 86225-ds-DNA Ab with Reflex (if appropriate), 86255-ds-DNA Ab by Crithidia IFA (if appropriate), 86235 x 6-RNP, Sm, SS-B, SS-A, Jo 1, and Scl 70 (if appropriate)

Last Updated: Thursday, January 5, 2017 03:42:05 AM