COPPER, URINE

Mnemonic

COPU

Guidelines

Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of their physician). High concentrations of iodine may interfere with elemental testing. Abstinence from iodine-containing medications or contrast agents for at least 1 month prior to collecting specimens for elemental testing is recommended.

Specimen Collection Requirements

Collect

24-hour or random urine collection. Specimen must be collected in a plastic container. Refrigerate urine during and after collection, preserves specimens adequately, if tested within 14 days of collection.

Handling

Transfer aliquot from a well-mixed collection to Trace Element-Free Transport Tubes Record total volume and collection time interval on transport tube and on test request form.

Preferred Volume

20

Minimum Volume

5

Transport

Refrigerated

Rejection Criteria

Urine collected within 48 hours after administration of a gadolinium (Gd) containing contrast media (may occur with MRI studies). Acid preserved urine.

Stability

Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 1 year

Testing Information

Performed

Mon-Sat

Reported

1-5 days

Method

Inductively Coupled Plasma/Mass Spectrometry

Referral Lab

ARUP 20461

Reference Values

Reference Values

Copper, Urine Copper, Urine (24-hour) Copper per gram of creatinine
0.2-8.0 µg/dL 3-50 µg/d No reference interval (µg/g crt)

CPT Codes

82525

Last Updated: Thursday, January 14, 2016 01:37:37 PM