EPSTEIN-BARR VIRUS PANEL

Mnemonic

EBVPAN

Synonym

EA-D IgG Ab - EBNA-IgG Ab - EBV Antibodies - EBV Antibody Panel - EBV VCA-IgG Ab - EBV VCA-IgM Ab - Infectious Mononucleosis Antibody Panel

Includes

Epstein-Barr Virus IgG Antibody to Early D Antigen
Epstein-Barr Virus IgG Antibody to Nuclear Antigen
Epstein-Barr Virus IgG Antibody to Viral Capsid Antigen
Epstein-Barr Virus IgM Antibody to Viral Capsid Antigen
 

Specimen Collection Requirements

Collect

Serum, one 5.0 mL gold (SST) or 7.0 mL red top tube

Handling

Allow serum to clot completely at room temperature (minimum – SST: 30 minutes, red top tubes: 60 minutes). Centrifuge and separate serum from cells ASAP.

Preferred Volume

2.0 mL Serum

Minimum Volume

0.5 mL (1.2 mL minimum whole blood draw)

Transport

Refrigerated (2-8°C)

Rejection Criteria

Grossly hemolyzed, icteric or lipemic specimens; heat inactivated specimens; plasma.

Stability

AFTER SEPARATION FROM CELLS:  Room temperature (18-26°C):  Unacceptable; Refrigerated (2-8°C):  6 days; Frozen (≤ -10°C):  21 days (not more than 3 freeze/thaw cycles).

Testing Information

Performed

Mon - Fri 

Reported

24 - 72 hours

Method

Chemiluminescent Immunoassay

Reference Values

Reference Values

EBV IgG Ab to Early D Ag:  
<=8.9 U/mL        Negative for Epstein-Barr Virus  Early Antigen (D) IgG Antibody

9.0-10.9 U/mL    Equivocal for Epstein-Barr Virus Early Antigen (D) IgG Antibody. Repeat testing in 7-10 days may be helpful.

>=11.0 U/mL      Positive for Epstein-Barr Virus Early Antigen (D) IgG Antibody.

EBV IgG Ab to Nuclear Ag:
<=17.9 U/mL        Negative for Epstein-Barr Virus Nuclear Antigen IgG Antibody.

18.0-21.9 U/mL    Equivocal for Epstein-Barr Virus Nuclear Antigen IgG Antibody. Repeat testing in 7-10 days may be helpful.

>=22.0 U/mL        Positive for Epstein-Barr Virus Nuclear Antigen IgG Antibody.

EBV IgG Ab to Viral Capsid Ag:
<=17.9 U/mL        Negative for Epstein-Barr Virus Viral Capsid Antigen IgG Antibody.

18.0-21.9 U/mL    Equivocal for Epstein-Barr Virus Viral Capsid Antigen IgG Antibody. Repeat testing in 7-10 days may be helpful.

>=22.0 U/mL        Positive for Epstein-Barr Virus Viral Capsid Antigen IgG Antibody.

EBV IgM Ab to Viral Capsid Ag:
<=35.9 U/mL        Negative for Epstein-Barr Virus Viral Capsid Antigen IgM Antibody.

36.0-43.9 U/mL    Equivocal for Epstein-Barr Virus Viral Capsid Antigen IgM Antibody. Repeat testing in 7-10 days may be helpful.

>=44.0 U/mL        Positive for Epstein-Barr Virus Viral Capsid Antigen IgM Antibody.

CPT Codes

86665 (X2), 86664, 86663

Last Updated: Thursday, January 5, 2017 03:42:09 AM