ETHOSUXIMIDE

Mnemonic

ETHO

Synonym

Zarontin®

Guidelines

For information on when to collect specimen, please refer to Therapeutic Drug Monitoring (TDM) Guidelines for Pediatrics and Adults

Specimen Collection Requirements

Patient Preparation

Trough levels are recommended. Reference ranges are based on trough levels. To obtain a trough level draw specimen just prior to next dose.<br />

Collect

Serum or Plasma, one 7.0 mL red, 4.0 mL dark green (sodium heparin), or 4.0 mL lavender (EDTA) top tube

Handling

Allow serum to clot completely at room temperature (minimum: 30 minutes). Centrifuge and separate serum or plasma within one hour of collection.

Preferred Volume

1 mL

Minimum Volume

0.25 mL serum or plasma (Whole Blood 1.0 mL minimum draw)

Transport

Refrigerated (2-8°C)

Rejection Criteria

Serum or Plasma exposed to gel barrier (SST or PST) for more than 24 hours, grossly hemolyzed specimens

Stability

Ambient (18-26°C): 14 days; Refrigerated (2-8°C): 14 days; Frozen (< -20°C): 14 days

Testing Information

Performed

7 days/week

Reported

24 hours

Method

Enzyme Immunoassay

Reference Values

Therapeutic Range

For Therapeutic Ranges, please refer to Therapeutic Drug Monitoring (TDM) Guidelines for Pediatrics and Adults

Toxic Levels

For Toxic Values, please refer to Therapeutic Drug Monitoring (TDM) Guidelines for Pediatrics and Adults

Comments

Ethosuximide levels will be falsely elevated in patients who are also taking Methsuximide (Celontin).

CPT Codes

80339

Last Updated: Thursday, January 5, 2017 03:42:10 AM