HIV PHENOSENSE

Mnemonic

HIV-1 PHEN

Synonym

Phenotype - HIV Phenotype

Guidelines

Direct measurement of the drug susceptibility of a patient’s HIV-1 virus to all approved antiretrovirals combined with identification of HIV-1 drug resistance mutations by sequencing. Procedure should be used for patients with documented HIV-1 infection and viral loads ≥500 copies/mL.

Specimen Collection Requirements

Patient Preparation

Must have a recent HIV viral load of >500 copies/mL. Viral loads should be collected either at the same time, or within two weeks prior to collection of HIV Phenotype.

Collect

Plasma, two lavender (EDTA) top tubes

Handling

Centrifuge within 6 hours and transfer to plastic screw-cap tube. Freeze immediately after centrifugation.

Minimum Volume

3.0 mL frozen plasma

Transport

Frozen

Rejection Criteria

Specimens other than EDTA plasma, specimens not frozen

Testing Information

Performed

7 days/week

Reported

14-16 days

Method

Drug Susceptibility using HIV Culture

Referral Lab

Monogram Biosciences (V3200)

Reference Values

Reference Values

Interpretation provided.

CPT Codes

87903, 87904 (x11)

Last Updated: Thursday, January 5, 2017 03:42:15 AM