LYME ANTIBODY SCREEN (IgG AND IgM)

Mnemonic

LYM

Synonym

Borrelia burgdorferi - Lyme Antibodies Detection - Lyme Disease - Lyme Disease Ab

Guidelines

Lyme disease is an infectious disease caused by the spirochete Borrelia burgdorferi, and is transmitted through the bite of one of several Ixodes species ticks.  Positives are NOT automatically reflexed for confirmation by Western Blot.  If Western Blot confirmation of positive is desired, order LYME SCREEN IGG/IGM REFLEX TO LYME WB.

Specimen Collection Requirements

Collect

Serum, one 5.0 mL gold (SST) or 7.0 mL red top tube

Handling

Allow serum to clot completely at room temperature (minimum – SST: 30 minutes, red top tubes: 60 minutes). Centrifuge and separate serum from cells ASAP.

Preferred Volume

1.0 mL

Minimum Volume

 0.5 mL Serum (1.2 mL minimum whole blood draw)

Transport

Refrigerated (2-8°C)

Rejection Criteria

Grossly hemolyzed, icteric or lipemic specimens; heat inactivated specimens; plasma

Stability

AFTER SEPARATION FROM CELLS:  Room temperature (18-26°C): Unacceptable; Refrigerated (2-8°C):  7 days; Frozen (≤ -20°C): Unacceptable.

Testing Information

Performed

Mon - Fri

Reported

24-72 hours

Method

Chemiluminescent Immunoassay

Reference Values

Reference Values

<= 0.89 Index Value         Negative for Borrelia burgdorferi antibodies.  A negative result does not exclude the possibility of Borrelia burgdorferi infection.  If early Lyme disease is suspected, a second sample should be collected and tested two to four weeks later.

0.90 – 1.09 Index Value   Equivocal for Borrelia burgdorferi antibodies.  Recommend Western Blot testing.

>=  1.10 Index Value               Positive for Borrelia burgdorferi antibodies.  Recommend Western Blot testing.
 

CPT Codes

86618

Last Updated: Thursday, January 5, 2017 03:42:20 AM