PRIMIDONE

Mnemonic

MYSO

Synonym

Mysoline®

Includes

Primidone metabolite (phenobarb)

Guidelines

For information on when to collect specimens, please refer to: Therapeutic Drug Monitoring (TDM) Guidelines for Pediatrics and Adults

Specimen Collection Requirements

Collect

Serum or Plasma, one 7.0 mL red, 4.0 mL dark green (sodium heparin), or 4.0 mL lavender (EDTA) top tube

Handling

Allow serum to clot completely at room temperature (minimum: 30 minutes). Centrifuge and separate serum or plasma within one hour of collection.

Preferred Volume

2 mL Serum or Plasma

Minimum Volume

0.25 mL (Whole Blood 1.0 mL minimum draw)

Transport

Refrigerated (2-8°C)

Rejection Criteria

Serum or Plasma exposed to gel barrier (SST or PST) for more than 24 hours, grossly hemolyzed specimens

Stability

Ambient (20-25°C): 72 hours; Refrigerated (2-8°C): 1 week; Frozen (at or below -20°C): 3 months

Testing Information

Performed

7 days/week

Reported

24 hours

Method

Enzyme immunoassay

Reference Values

Last Updated: Thursday, January 5, 2017 03:42:25 AM