PROCALCITONIN

Mnemonic

PCT

Guidelines

For a given patient, the PCT assays must be performed on the same type of sample tube

Specimen Collection Requirements

Collect

One Li Heparin PST or One SST Tube

Preferred Volume

1.0 mL

Minimum Volume

0.5 mL

Transport

Refrigerated

Stability

2-8C up to 48 hours or -25C up to six months (3 freeze/thaw cycles validated)

Testing Information

Note

PCT is the prohormone of calcitonin and is not normally present in the bloodstream of a healthy individual. PCT is released from multiple organs when there is a systemic bacterial infection. The blood level of PCT is a reflection of the severity of bacterial infection, ranging from slightly elevated concentrations in infections with minor systemic inflammatory response to very high values in cases of severe sepsis and septic shock.

Performed

As Received

Method

Immunofluorescent

Referral Lab

Samaritan Health Services Laboratories-SAGH

Reference Values

Reference Values

PCT <0.5 ng/ml Systemic infection (sepsis) is not likely Local bacterial infection is possible Low risk for progression to severe systemic infection (severe sepsis) Caution: PCT levels below 0.5 ng/ml do not exclude an infection, because localized infections (without systemic signs) may be associated with such low levels. Also if the PCT measurement is done very early after following bacterial challenge (usually <6 hours), these values may still be low. In this case, PCT should be re-assessed 6-24 hours later. Low risk for progression to severe systemic infection (severe sepsis). ============================================================================== PCT >0.5 and <2 ng/ml Systemic infection (sepsis) is possible, but various conditions are known to induce PCT as well. Moderate risk for progression to severe systemic infection (severe sepsis). The patient should be closely monitored both clinically and by re-assessing PCT within 6-24 hours. ============================================================================== PCT >2 and <10 ng/ml Systemic infection (sepsis) is likely, unless other causes are known. High risk for progression to severe systemic infection (severe sepsis). ============================================================================== PCT >10 ng/ml Important systemic inflammatory inflammatory response, almost exclusively due to severe bacterial sepsis or septic shock. High likelihood of severe sepsis or septic shock. ==============================================================================

CPT Codes

84145

Last Updated: Thursday, January 5, 2017 03:42:26 AM