WEST NILE VIRUS ANTIBODIES, IgG & IgM, CSF

Mnemonic

MISC

Synonym

CSF West Nile Virus Antibodies

Guidelines

Test used to detect IgG and IgM antibodies to West Nile virus in CSF samples.

Specimen Collection Requirements

Collect

CSF in sterile container

Preferred Volume

2.0 mL

Minimum Volume

0.5 mL, pediatric: 0.3 mL

Transport

Refrigerated

Rejection Criteria

Heat inactivated, contaminated or hemolyzed specimens

Stability

Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: 1 year, avoid repeated freeze/thaw cycles

Testing Information

Performed

Sun, Tue, Fri

Reported

2-7 days

Method

Enzyme-Linked Immunosorbent Assay

Referral Lab

ARUP (50228)

Reference Values

Reference Values

Interpretation provided.

Comments

Detection of West Nile virus antibodies in CSF may indicate central nervous system infection. However, consideration must be given to possible contamination by blood or transfer of serum antibodies across the blood-brain barrier. Because other members Flaviviridae, such as St. Louis encephalitis virus or Dengue Fever virus, show extensive cross-reactivity with West Nile virus, serologic testing specific for these species should also be considered.

CPT Codes

86788, 86789

Last Updated: Thursday, January 5, 2017 03:42:34 AM