ZINC PROTOPORPHYRIN Mnemonic FEP Synonym Zinc Protoporphyrins Whole Blood – ZnPP - ZPPH Includes Zinc Protoporphyrin, Blood Zinc Protoporphyrin (ZPP), Whole Blood Ratio Specimen Collection Requirements Collect EDTA Whole Blood, one 4.0 mL lavender (EDTA), 6.0 mL royal blue (K2EDTA or Na2EDTA), or 3.0 mL tan (K2EDTA) top tube Use royal blue top tube when also testing for lead. Handling Guard the specimen against environmental contamination. Keep the specimen sealed in the original container. Do not separate the plasma from the red blood cells. Preferred Volume 1.0 mL EDTA Whole Blood Minimum Volume 0.2 mL EDTA Whole Blood Transport Refrigerated (2-8 ºC) Rejection Criteria Specimens other than EDTA whole blood Hemolyzed specimens Clotted specimens Frozen specimens Stability Room Temperature (18-26°C): 30 hours; Refrigerated (2-8°C): 5 weeks; Frozen (≤ -20°C): Unacceptable Testing Information Performed Mon-Fri Reported 2-5 days Method Hematofluorometry Referral Lab ARUP 0020614 Reference Values Reference Values ZPP: 0-40 µg/dL ZPP/Heme Ratio: 0-69 µmol ZPP/mol heme Comments For occupational exposure to lead, OSHA requires ZPP whole blood concentration to be reported in units of µg/dL. For adults, conversion of ZPP to units of µg/dL assumes a hematocrit of 45%. CPT Codes 84202 Last Updated: Thursday, January 5, 2017 03:42:34 AM