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ANA-12 Profile

Mnemonic

ANA 12

Synonym

ANA Screen with Reflex to Titer and Pattern - Lupus Panel 4

Includes

ANA Screen, IFA with Reflex to Titer and Pattern, Complement Component C3c and C4c, DNA (ds) Antibody, Ribosomal P Antibody, Sm Antibody, Sm/RNP Antibody, Sjogren’s Antibodies (SS-A, SS-B), Thyroid Peroxidase Antibody (TPO), Scleroderma Antibody (Scl-70), Rheumatoid Factor

Specimen Collection Requirements

Collect

Serum, one 5.0 mL gold (SST) or 7.0 mL red top tube

Supply Item Number – 101235 or 101192

Handling

Allow serum to clot completely at room temperature (minimum for SST: 30 minutes; minimum for red top tubes: 60 minutes).

Centrifuge and separate serum from cells immediately.

Preferred Volume

4 mL Serum

Minimum Volume

2 mL Serum

Transport

Frozen (at or below -20°C)

Rejection Criteria

Grossly hemolyzed, grossly lipemic, grossly icteric, specimens that are not received frozen.

Stability

AFTER SEPARATION FROM CELLS: Ambient: Unacceptable; Refrigerated (2-8oC): Unacceptable; Frozen (at or below -20oC): 21 days

Testing Information

Performed

Mon - Fri

Reported

2-5 days

Method

Immunoassay (IA), Immunoturbidimetric Assay

Referral Lab

Quest Diagnostics (10716)

Reference Values

Reference Values

Component

Reference Values

Interpretation

Absolute

ANA Screen, IFA with Reflex to Titer and Pattern

Negative

 

Complement Component C3c

Not Established

83-193 mg/dL

Complement Component C4c

Not Established

15-57 mg/dL

DNA (ds) Antibody

Negative

<5 IU/mL

Ribosomal P Antibody

Negative

<1.0 AI

Sm Antibody

Negative

<1.0 AI

Sm/RNP Antibody

Negative

<1.0 AI

Sjogren’s Antibodies (SS-A, SS-B)

Negative

<1.0 AI

Thyroid Peroxidase Antibody (TPO)

 

<9 IU/mL

Scleroderma Antibody (Scl-70)

Negative

<1.0 AI

Rheumatoid Factor

 

<14 IU/mL

CPT Codes

83516, 86038, 86160 (x2), 86225, 86235 (x5), 86376, 86431

Last Updated: Monday, October 21, 2019 07:45:22 PM


Client Services: 503-413-1234