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C Difficile Toxin by PCR

Mnemonic

CD TOXIN PCR

Synonym

Clostridium Difficile Toxin by PCR

Guidelines

This FDA approved assay detects the toxin B gene sequence of Clostridium difficile. Testing for C. difficile should be limited to patients with appropriate signs and symptoms of C. difficile-associated disease, as some people may be asymptomatically colonized with toxigenic C. difficile. This test is only for patients of at least 2 years of age.

Please see Laboratory Testing Algorithm for Infectious Causes of Diarrhea.

Specimen Collection Requirements

Collect

Fresh unformed stool in a leak-proof container or unformed stool in Enteric Transport Media

View Stool Collection Guide

Patient Instructions for Special Stool Testing - English

Only Bristol Type 6 or Bristol Type 7 are acceptable for this test. Please click here to see Bristol Stool Chart.

Preferred Volume

5.0 mL

Minimum Volume

2.0 mL

Transport

Refrigerated

Rejection Criteria

Formed stools, stool preserved in PVA, SAF or formalin, frozen, specimens past stability, rectal swabs

Stability

Ambient: 1 hour; Refrigerated: 3 days

Testing Information

Note

Tests sent on formed stools, repeat testing within 14 days from last positive, or repeat testing within 7 days from last negative result of the original test will be rejected.  Testing on asymptomatic patients, patients given a laxative, or for proof-of-cure is discouraged.  Exceptions will be made on a case by case basis by contacting the Microbiology laboratory at 503-413-4084.

Performed

7 days/week

Reported

Within 24 hours of receipt

Method

PCR

Reference Values

Reference Values

Negative

CPT Codes

87493

Last Updated: Wednesday, December 16, 2020 12:53:29 AM


Client Services: 503-413-1234