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Chromosomal Analysis Solid Tumors

Synonym

Karyotype - Karyotyping - Chromosomes - Chromosome Study - Cytogenetics

Guidelines

Chromosome abnormalities may assist in the identification and classification of malignant tumors.

Specimen Collection Requirements

Collect

Biopsy, obtained using sterile technique

Handling

Place specimen in a screw-top container and cover with sterile Hanks BSS, normal saline or RPMI transport media. The volume of transport media should be sufficient to keep the specimen from drying out. Do not expose to, or place in, formalin. Keep specimen at ambient temperature and transport within 24 hours. To obtain best results, the specimen needs to processed the same day as collected and always within 24 hours. STAT delivery is recommended. See Cytogenetics/Flow Cytometry/FISH Specimens for Leukemia, Lymphoma and Other Oncology Referrals.

Minimum Volume

Approximately 1.0 cm3

Transport

Room temperature within 24 hours

Rejection Criteria

SPECIMENS SUBMITTED IN OR EXPOSED TO FORMALIN. Rejection is only at the discretion of the Cytogenetics Laboratory.

Stability

Ambient: 24 hours; Refrigerated: Suboptimal, call Cytogenetics Lab at (503) 413-4613

Testing Information

Note

Clinical information including the indication for study must accompany the specimen. Requisition forms for cytogenetics studies are available upon request.

Performed

7 days/week

Reported

3-4 weeks

Method

Classical G-Band Chromosomal Analysis

Reference Values

Reference Values

Cytogenetics interpretation provided. A computer generated karyotype is also provided with each study.
Normal range:
46,XX [number of cells analyzed], apparently normal female
46,XY [number of cells analyzed], apparently normal male

Comments

For questions regarding the report, please call (503) 413-4613.

Last Updated: Friday, January 17, 2020 12:19:09 AM


Client Services: 503-413-1234