Blood cobalt levels can be used in the assessment of occupational exposure or toxic ingestion. Symptoms associated with cobalt toxicity vary based on route of exposure and may include cardiomyopathy, allergic dermatitis, pulmonary fibrosis, cough and dyspnea. Serum is the preferred specimen type for evaluating metal ion release from metal-on-metal joint arthroplasty.
Specimen Collection Requirements
Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of their physician).
Whole Blood, one royal blue (K2EDTA or Na2 EDTA) top tube
Transport 7.0 mL whole blood in the original collection tube
Heparin anticoagulant or frozen specimens
If the specimen is drawn and stored in the appropriate container, the trace element values do not change with time.
Quantitative Inductively Coupled Plasma-Mass Spectrometry
Thursday, March 14, 2019 12:50:31 PM
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