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Cryoprecipitate

Blood Product

Description

One bag (6.0-15.0 mL) provides ≥80 units Factor VIII and ≥150 mg fibrinogen

Patient Preparation

Fibrinogen and PTT results are needed to document indication and to monitor therapeutic response. Patient must be properly identified before blood product administration. See the LHS Blood Administration policy.

Storage

Frozen at <-18°C. Thawed product stored at room temperature (20-24°C).

Expiration

1 year if frozen; 6 hours if thawed

Reported

A minimum of 20 minutes.

Comment

A crossmatch is not necessary. ABO compatibility is not essential in adults. Allow 10 minutes to thaw.

Use

To control bleeding associated with uremia, factor XIII, fibrinogen and fibronectin deficiencies. Can be used to treat Hemophilia A if Factor VIII concentrate is not available, and von Willebrand's Disease if factor VIII concentrate containing VW Factor is not available.

Transfusion Guidelines and Audit Criteria for Infants Less than Four Months of Age

Transfusion Guidelines and Audit Criteria for Pediatric Patients Greater than Four Months

 

Transfusion Guidelines for Adults

Limitations

Consider alternative therapy. Factor VIII concentrate is the preferred therapy for hemophilia A and for von Willebrand's disease.

Dosage

Usual adult hemostatic dose is 8-10 bags, which should raise fibrinogen levels by 70-100 mg/dL. If fibrinogen <50 mg/dL give 20 units.

Administration

Transfuse 5-10 mL/minute or as patient tolerates. Must be administered with an in-line (170-260 micron) filter.

Last Updated: Friday, November 29, 2019 09:35:21 PM


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