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* D-Dimer, Quantitative, High Sensitivity

Mnemonic

DDQ HS

Synonym

DDQ - D-Dimer - Ddimer - D dimer - DDQ HS

Guidelines

Indicated for use in conjunction with a clinical pretest probability assessment model to exclude deep vein thrombosis (DVT) and pulmonary embolism (PE) and as an aid in the diagnosis of disseminated intravascular coagulation (DIC).

Specimen Collection Requirements

Collect

Whole Blood, one light blue (3.2% Buffered Sodium Citrate) top tube

Handling

See Coagulation Specimen Collection Guidelines.

Due to the short stability of the specimen, whole blood specimen tubes must reach the testing department within 4 hours, otherwise submit frozen plasma aliquots. NOTE: Frost-free refrigerator freezers are not acceptable for frozen sample storage. If proper storage is unavailable at the collection site, freeze/store aliquots on dry ice. Alternatively, send the patient to the nearest Legacy Hospital Outpatient Lab for sample collection/processing.

If submitting whole blood, transport at ambient temperature (15-25°C) in original unopened tube. If submitting frozen plasma aliquots, specimens must remain frozen (-20°C) during transport.

Preferred Volume

2.7 mL whole blood or two 1.0 mL frozen plasma aliquots

Minimum Volume

1.8 mL whole blood or one 1.0 mL frozen plasma aliquot

Transport

Whole Blood: Ambient (15-25°C)

Plasma: Frozen, aliquot must remain frozen during storage and shipment

Rejection Criteria

Whole Blood Refrigerated (2-8°C), clotted samples, samples collected in containers other than 3.2% Buffered Sodium Citrate, tubes filled less than 90%, samples from patients with a Hematocrit greater than 55%, hemolyzed samples due to ex-vivo causes (i.e., difficult draw, poor sample draw), whole blood samples that were frozen before processing

Stability

WHOLE BLOOD: Ambient: 4 hours

PLASMA: Ambient: 4 hours; Frozen (-20°C): 2 weeks, Frozen (-70°C): 6 months

Testing Information

Performed

7 days/week

Reported

2 hours

Method

Turbidimetric Immunoassay

Reference Values

Reference Values

0-229 ng/mL D-DU

Comments

A value of less than 230 ng/mL D-DU is used in conjunction with a clinical pre-test probability assessment to exclude VTE in outpatients suspected of DVT and PE.

CPT Codes

85379

Last Updated: Wednesday, July 24, 2019 06:11:55 PM

Client Services: 503-413-1234