FISH Probe: ETV6/RUNX1-ES (TEL/AML1-ES)
t(12;21)(p13;q22) - ETV6/RUNX1 ES
This probe detects the t(12;21) seen in pediatric precursor B-lineage ALL and confers a favorable prognosis. This chromosomal abnormality is considered cryptic by conventional cytogenetics, thus reinforces the need to perform this test. Amplification of AML1, which is associated with a poor outcome, is also detectable by this probe set.
Specimen Collection Requirements
Fluorescence In Situ Hybridization
Professional interpretation provided by Cascade Pathology Services.
This probe is part of the Pediatirc Acute Lymphoblastic Leukemia Panel, probes can be ordered individually.
Saturday, January 18, 2020 01:04:15 AM
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