This probe is designed to detect translocations/variant rearrangements and partial or complete deletions of IGH gene on chromosome 14 at q32.2 region. The heavy chain locus is involved with nonrandom chromosomal rearrangements that characterize B-cell neoplasais, lymphomas, MM, HCL.
Specimen Collection Requirements
Fluorescence In Situ Hybridization (FISH)
Professional interpretation provided by Cascade Pathology Services.
The partner chromosome of translocation can be determined by metaphase FISH, wherever applicable. This probe is part of the Multiple Myeloma Panel, probes can be ordered individually.
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