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FISH PROBE: MYCN/CEP2

Mnemonic

ADULT: ATTN FISH, PEDIATRIC: ATTN CYGEN

Synonym

2p24/2p11.1-q11.1 - N-MYC/CEP2

Guidelines

This probe set detects amplification of MYCN gene in neuroblastoma and is able to differentiate amplification versus hyperdiploidy of chromosome 2. Amplification is associated with an adverse prognostic feature and poor prognosis.

Specimen Collection Requirements

Handling

For detailed collection and handling information, refer to Cytogenetics, Flow Cytometry and FISH Specimens for Leukemia, Lymphoma and Other Oncology Referrals.

Testing Information

Performed

Mon - Fri

Reported

7 days

Method

Fluorescence In Situ Hybridization (FISH)

Reference Values

Reference Values

Professional interpretation provided by Cascade Pathology Services.

Comments

Assessment of MYCN amplification is a quick, reliable and an essential component of the routine diagnostic evaluation of new neuroblastoma patients and follow-up.

CPT Codes

ADULT: 88377 x 1

Last Updated: Thursday, March 14, 2019 12:50:41 PM

Client Services: 503-413-1234