(17p13.1)/(11q22.3)/(6q23) - P53/ataxia telangiectasia mutated/MYBC
This tricolor probe set detects deletions of: TP53 gene on chromosome 17 at 17p13 region, ATM gene on chromosome 11 at 11q22-23 region and MYB on chromosome 6 at q23 region. These deletions are associated with B-cell chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL). Deletions of 17p and 11q are associated with an adverse clinical outcome, with poor and short survival. Deletions of 6q are known to be the fourth most common chromosome aberrations in B-CLL.
Specimen Collection Requirements
Fluorescence In Situ Hybridization (FISH)
Professional interpretation provided by Cascade Pathology Services.
This probe is part of the Chronic Lymphocytic Leukemia Panel, probes can be ordered individually.
Thursday, March 14, 2019 12:50:42 PM
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