ADULT: ATTN FISH, PEDIATRIC: ATTN CYGEN
(17p13.1)/(17p11.1-q11.1) - P53/CEP17
This probe detects deletions (not mutations) of P53 gene on chromosome 17 at 17p13.1 region. This deletion is observed in multiple myeloma patients and has been associated with adverse prognosis. Loss of heterozygosity of P53 has also been identified in many tumors.
Specimen Collection Requirements
Fluorescence In Situ Hybridization (FISH)
Professional interpretation provided by Cascade Pathology Services.
Order the Chronic Lymphocytic Leukemia Panel for P53 deletions in CLL cases. This probe is part of the Multiple Myeloma Panel, probes can be ordered individually.
Thursday, March 14, 2019 12:50:42 PM
Client Services: 503-413-1234