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FISH PROBE: TP53/CEP17

Mnemonic

ADULT: ATTN FISH, PEDIATRIC: ATTN CYGEN

Synonym

(17p13.1)/(17p11.1-q11.1) - P53/CEP17

Guidelines

This probe detects deletions (not mutations) of P53 gene on chromosome 17 at 17p13.1 region. This deletion is observed in multiple myeloma patients and has been associated with adverse prognosis. Loss of heterozygosity of P53 has also been identified in many tumors.

Specimen Collection Requirements

Handling

Testing Information

Performed

Mon - Fri

Reported

7 days

Method

Fluorescence In Situ Hybridization (FISH)

Reference Values

Reference Values

Professional interpretation provided by Cascade Pathology Services.

Comments

Order the Chronic Lymphocytic Leukemia Panel for P53 deletions in CLL cases.   This probe is part of the Multiple Myeloma Panel, probes can be ordered individually.

CPT Codes

ADULT: 88377 x 1

Last Updated: Thursday, March 14, 2019 12:50:42 PM


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