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HYPERCOAGULATION PANEL

Mnemonic

HYPER COAG

Synonym

Hypercoag Panel - Thrombophilia Panel - Thrombotic Risk Panel

Includes

Antithrombin III Activity, Fibrinogen, Protein C Activity, PT/PTT, Thrombin Time

Specimen Collection Requirements

Patient Preparation

The test is not recommended if the patient is on anticoagulant therapy.

Collect

Whole Blood light blue top tube (3.2% Buffered Sodium Citrate)

Handling

Patients should not be on heparin or coumadin therapy. If therapy is unavoidable, then note on the requisition that the patient is on heparin or coumadin therapy. 
Due to short stability, whole blood specimen tubes must reach the testing department within 4 hours, otherwise submit frozen plasma aliquots. NOTE: Frost-free refrigerator freezers are not acceptable for frozen sample storage. If proper storage is unavailable at the collection site, freeze/store aliquots on dry ice. Alternatively, send the patient to the nearest Legacy Hospital Outpatient Lab for sample collection/processing.

If submitting whole blood, transport at ambient temperature (15-25°C) in original unopened tube. If submitting frozen plasma aliquots, specimens must remain frozen (-20°C) during transport.

Preferred Volume

Three 2.7 mL whole blood or four 1.0 mL frozen plasma aliquots

Minimum Volume

Two 2.7 mL whole blood or three 1.0 mL frozen plasma aliquot

Transport

Whole Blood: Ambient (15-25°C) 

Plasma: Frozen (-20°C), aliquots must remain frozen during storage and transport

Rejection Criteria

Whole Blood or Plasma, Refrigerated (2-8°C), clotted samples, samples collected in containers other than 3.2% Buffered Sodium Citrate, tubes filled less than 90%, samples from patients with a Hematocrit greater than 55%, hemolyzed samples due to ex-vivo causes (i.e., difficult draw, poor sample draw), whole blood samples that were frozen before processing

Stability

WHOLE BLOOD: Ambient: 4 hours

PLASMA: Ambient: 4 hours; Frozen: -20°C 2 weeks, -70°C 6 months

Testing Information

Performed

Daily, Mon-Friday

Reported

1 week

Method

Chromogenic, Clotting

Reference Values

Reference Values

See individual test.

CPT Codes

85300, 85384, 85303, 85610, 85730, 85670

Last Updated: Thursday, March 14, 2019 12:50:49 PM


Client Services: 503-413-1234