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Lead, Industrial Exposure Panel, Adult

Mnemonic

LEAD WB IND

Synonym

Lead Exposure - Blood Lead Level - BLL - Venous Blood Lead - ZnPP - ZPP

Includes

  • Zinc Protoporphyrin, Blood
  • Zinc Protoporphyrin (ZPP), Whole Blood Ratio
  • Lead, Industrial, Whole Blood

Guidelines

Recommended for the assessment of industrial lead exposure in adults and provides exposure guidance in accordance with OSHA regulations. To assess lead exposure in a non-occupational setting, order either Lead, Whole Blood or Zinc Protoporphyrin

Specimen Collection Requirements

Patient Preparation

Collect from patient aged 16 years or older.

Collect

EDTA Whole Blood, one certified lead-free tube such as one 6.0 mL royal blue (K2EDTA or Na2EDTA) or 3.0 mL tan (K2EDTA) top tube

NO LAVENDER TOP TUBES 

Handling

Guard the specimen against environmental contamination. Keep the specimen sealed in the original container. Do not separate the plasma from the red blood cells.

Preferred Volume

7.0 mL EDTA Whole Blood

Minimum Volume

2.0 mL EDTA whole blood

Transport

Refrigerated (2-8 ºC)

Rejection Criteria

  • Whole blood collected in tube other than royal blue (K2EDTA or Na2EDTA) or tan (K2EDTA) top
  • Serum or plasma specimens
  • Hemolyzed specimens
  • Clotted specimens
  • Frozen specimens

Stability

Room Temperature (18-26°C): 30 hours; Refrigerated (2-8°C): 5 weeks; Frozen (≤ -20°C): Unacceptable

Testing Information

Note

Elevated blood lead levels may be due to skin or collection-related contamination, including use of non-certified lead free tubes. Elevated levels of blood lead should be confirmed with a second specimen collected in a lead-free tube. 

Performed

Sun-Sat

Reported

2-6 days

Method

Hematofluorometry, Inductively Coupled Plasma-Mass Spectrometry

Referral Lab

ARUP 0025016

Reference Values

Reference Values

Lead: 0-4.9 µg/dL

 

 

Toxic Levels

ZPP: See Zinc Protoporphyrin

ZPP/ Heme Ratio: See Zinc Protoporphyrin

Lead:  See ARUP report

Comments

For occupational exposure to lead, OSHA requires ZPP whole blood concentration to be reported in units of µg/dL. For adults, conversion of ZPP to units of µg/dL assumes a hematocrit of 45%.

All blood lead levels are reported to the Oregon or Washington Health Division.

CPT Codes

Lead: 83655, ZPP: 84202

Last Updated: Wednesday, January 20, 2021 01:35:35 AM


Client Services: 503-413-1234