Levetiracetam, Quantitative, Serum or Plasma Mnemonic LEVET Synonym KeppraTM Specimen Collection Requirements Collect Serum or Plasma, one 7.0 mL red, 4.0 mL dark green (sodium heparin) or 4.0 mL lavender (EDTA) top tube Handling Allow serum to clot completely at room temperature (minimum: 30 minutes). Centrifuge and separate serum or plasma from cells ASAP. Preferred Volume 3 mL serum or plasma Minimum Volume 1 mL serum or plasma (Whole Blood 2.5 mL minimum draw) Transport Refrigerated ( 2-8°C) Rejection Criteria Specimens collected in gel separator tubes (PST or SST), gross hemolysis Stability AFTER SEPARATION FROM CELLS: Ambient (20-25 °C): 1 week; Refrigerated (2-8°C): 1 week; Frozen (at or below -20°C): 2 weeks. Avoid repeat freeze/thaw cycles. Testing Information Performed Sun, Tue, Thur Reported 1-4 days Method Liquid Chromatography Tandem Mass Spectrometry Reference Values Therapeutic Range Please see Therapeutic Drug Monitoring (TDM) Guidelines for Pediatrics and Adults Toxic Levels Please see Therapeutic Drug Monitoring (TDM) Guidelines for Pediatrics and Adults CPT Codes 80177 Last Updated: Friday, June 21, 2019 12:35:26 AM Client Services: 503-413-1234