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* Prenatal Screen, Alphafetoprotein, Amniotic Fluid

Mnemonic

AFAFP

Synonym

Amniotic Fluid Alpha fetoprotein - Amniotic Fluid AFP - AF AFP

Includes

Amniotic Fluid AFP, Neural Tube Defect Risk

Guidelines

Submit specimen with all completed clinical information on the Prenatal Screening Requisition (Click here to view/print form). The following information is required: patient’s date of birth, patient’s ethnicity, estimated date of delivery, dating method (LMP or US), number of fetuses present, medication dependent diabetic, smoking status, previous pregnancy history with ONTD, and for IVF pregnancies, the birthdate or age of the egg donor.

Specimen Collection Requirements

Patient Preparation

Specimen must be drawn between 15 weeks, 0 days to 22 weeks, 6 days gestation. Patient history is required.

Collect

Amniotic Fluid, one sterile container

Handling

Submit specimen with Prenatal Screening Requisition.

Preferred Volume

1.0 mL Amniotic Fluid

Minimum Volume

0.5 mL Amniotic Fluid

Transport

Refrigerated (2-8°C)

Rejection Criteria

  • Specimens collected outside 15 weeks, 0 days to 22 weeks, 6 days gestation
  • Grossly hemolyzed specimens

Stability

AFTER SEPARATION FROM CELLS: Room Temperature (18-26°C): 8 hours; Refrigerated (2-8°C): 48 hours; Frozen (≤ - 20°C): 2 months.

Testing Information

Performed

Mon - Sat

Reported

24-72 hours

Method

Chemiluminescent Immunoassay

Reference Values

Reference Values

Interpretation provided

Comments

Positive Amniotic Fluid AFP risk results will automatically reflex to Acetylcholinesterase Amniotic Fluid

CPT Codes

82106

Last Updated: Thursday, February 11, 2021 06:19:21 PM


Client Services: 503-413-1234