Please see Syphilis Testing Algorithms
Order test if the following were performed at a separate laboratory:
1.) Confirming reactive quantitative non-Treponemal screen (i.e., RPR with titer) in the “Traditional” algorithm
or
2.) Confirming non-reactive non-Treponemal tests (i.e. RPR) that were originally screened reactive by immunoassay in the “Reverse” algorithm.
Testing by TPPA assumes that screening was performed at a separate laboratory. In the “Traditional” algorithm, TP-PA is recommended to confirm reactive non-Treponemal tests (i.e., RPR). In the “Reverse” algorithm, TP-PA is recommended to confirm non-reactive non-Treponemal tests (i.e., RPR) that were originally screened by immunoassay.